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During telophase, one of the key processes is the disassembly of spindle fibers. This is an essential part of cell division, specifically in the mitotic phase where the chromosomes that have been separated into two distinct sets begin to reorganize. As the spindle fibers break down, the cell prepares to wrap each set of chromosomes in a new nucleus.

Additionally, during telophase, the chromosomes start to de-condense back into chromatin, nuclear envelopes form around the separated chromosome sets, and the overall structure of the cell prepares for division into two distinct cells. While other phases like metaphase and anaphase involve the alignment and separation of chromosomes, telophase focuses on concluding these actions by establishing two nuclei, signaling an end to the chromosome segregation process initiated in earlier phases.

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